The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race

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The bestselling author of Leonardo da Vinci and Steve Jobs returns with a compelling (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didnt become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the books author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses What a wonderful boon that would be! And what about preventing depression HmmmShould we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an enthralling detective story (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.

Author Bio

Walter Isaacson is the bestselling author ofThe Code Breaker; Leonardo da Vinci;The Innovators;Steve Jobs;Einstein: His Life and Universe;Benjamin Franklin: An American Life;andKissinger: A Biography,and the coauthor ofThe Wise Men: Six Friends and the World They Made. He is a professor of history at Tulane and was CEO of the Aspen Institute, chair of CNN, and editor ofTime.Isaacson was awarded the National Humanities Medal in 2023. Visit him at Isaacson.Tulane.edu.